Title : CBL mutations in myeloproliferative neoplasms are also found in the gene's proline-rich domain and in patients with the V617FJAK2.

Pub. Date : 2012 Aug

PMID : 22315494






2 Functional Relationships(s)
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1 CBL mutations in myeloproliferative neoplasms are also found in the gene"s proline-rich domain and in patients with the V617FJAK2. Proline Cbl proto-oncogene Homo sapiens
2 RESULTS: An initial screening of all coding exons of CBL, CBLB and CBLC in 44 V617FJAK2-negative samples revealed two new CBL mutations (p.C416W in the RING finger domain and p.A678V in the proline-rich domain). Proline Cbl proto-oncogene Homo sapiens