Title : CBL enhances breast tumor formation by inhibiting tumor suppressive activity of TGF-β signaling.

Pub. Date : 2012 Dec 13

PMID : 22310290






1 Functional Relationships(s)
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Sentence
Compound Name
Protein Name
Organism
1 CBL directly binds to Smad3 through its proline-rich motif, thereby preventing Smad3 from interacting with Smad4 and blocking nuclear translocation of Smad3. Proline Cbl proto-oncogene Homo sapiens