Title : Retinoic acid regulates germ cell differentiation in mouse embryonic stem cells through a Smad-dependent pathway.

Pub. Date : 2012 Feb 17

PMID : 22293198






1 Functional Relationships(s)
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1 In a monolayer culture, RA significantly induced both the expression of the early germ-specific genes, Stra8, Dazl and Mvh, and prolonged activation of Smad1/5 (for at least 24h). Tretinoin stimulated by retinoic acid gene 8 Mus musculus