Title : Reconstitution of leucine-mediated autophagy via the mTORC1-Barkor pathway in vitro.

Pub. Date : 2012 Feb 1

PMID : 22258093






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1 Hence, we establish a novel cell-free assay recapitulating leucine-mediated autophagy inhibition in an mTORC1-dependent manner; this assay will help us to dissect the regulation of amino acids in autophagy and related human metabolic diseases. Leucine CREB regulated transcription coactivator 1 Mus musculus