Title : Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I.

Pub. Date : 2012 Jul

PMID : 22252477






1 Functional Relationships(s)
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1 When an anti-human CD20 antibody protein is stably expressed in one CHO-DUKX-Lec1 line, it is confirmed that N-glycans are predominantly Man(5) GlcNAc(2) and they do not contain an alpha1,6-fucose linked to the innermost GlcNAc. alpha1,6-fucose keratin 20 Homo sapiens