Title : Enhanced apoptosis-inducing function of MDA-7/IL-24 RGD mutant via the increased adhesion to tumor cells.

Pub. Date : 2012 Feb

PMID : 22248086






1 Functional Relationships(s)
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1 However, the apoptosis induction capacity of mda-7/IL-24 was low and directly correlated with the adhesion to tumor cells.Cell adhesion molecule integrin alpha(v)beta(3) expressed on the surface of several types of solid tumor cells, and they bind to arginine-glycine-aspartic acid (RGD) which enhanced the adhesion to tumor cells. arginyl-glycyl-aspartic acid integrin subunit alpha V Homo sapiens