Pub. Date : 2012 Feb 1
PMID : 22240591
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | A ubiquitin-like system mediates the conjugation of the C terminus of Atg8 to the lipid phosphatidylethanolamine (PE), and this conjugate (Atg8-PE) plays a crucial role in autophagosome formation at the phagophore assembly site/pre-autophagosomal structure (PAS). | Aminosalicylic Acid | ubiquitin-like protein ATG8 | Saccharomyces cerevisiae S288C |
| 2 | A ubiquitin-like system mediates the conjugation of the C terminus of Atg8 to the lipid phosphatidylethanolamine (PE), and this conjugate (Atg8-PE) plays a crucial role in autophagosome formation at the phagophore assembly site/pre-autophagosomal structure (PAS). | Aminosalicylic Acid | ubiquitin-like protein ATG8 | Saccharomyces cerevisiae S288C |
| 3 | We find that Atg8-PE accumulates on various organelle membranes including the vacuole, the endosome and the ER in these cells, which depletes unlipidated Atg8 and thereby attenuates its localization to the PAS. | Aminosalicylic Acid | ubiquitin-like protein ATG8 | Saccharomyces cerevisiae S288C |