Title : Copper-induced immunotoxicity involves cell cycle arrest and cell death in the spleen and thymus.

Pub. Date : 2012 Mar 11

PMID : 22239859






1 Functional Relationships(s)
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1 In conclusion, these studies show that sublethal exposure to copper (as copper chloride) induces toxicity in the thymus and spleen, and increased Sub G0/G1 population among splenocytes and thymocytes that is mediated, in part, by the EndoG-Bax-ubiquitin pathway. cupric chloride BCL2-associated X protein Mus musculus