Title : Thioesters for the in vitro evaluation of agents to image brain cholinesterases.

Pub. Date : 2013 Jun

PMID : 22233541






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1 Here, we report the synthesis and evaluation of a series of N-methylpiperidinyl thioesters, possessing comparable properties to their corresponding esters, which can be directly evaluated for cholinesterase kinetics and histochemical distribution in human brain tissue. Esters butyrylcholinesterase Homo sapiens