Pub. Date : 2012
PMID : 22223347
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | The administration of fibrates (fenofibrate, bezafibrate and clofibric acid) to rats induced stearoyl-CoA desaturase (SCD) in the liver, and increased relative expression of mRNAs encoding SCD1 and SCD2 in dose- and time-dependent manners. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
2 | The administration of fibrates (fenofibrate, bezafibrate and clofibric acid) to rats induced stearoyl-CoA desaturase (SCD) in the liver, and increased relative expression of mRNAs encoding SCD1 and SCD2 in dose- and time-dependent manners. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
3 | The administration of fibrates (fenofibrate, bezafibrate and clofibric acid) to rats induced stearoyl-CoA desaturase (SCD) in the liver, and increased relative expression of mRNAs encoding SCD1 and SCD2 in dose- and time-dependent manners. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |
4 | The magnitudes of the increases in SCD2 mRNA level caused by fenofibrate and clofibric acid were much higher than those of SCD1 at relatively higher doses of the fibrates, and a relatively long time (7 or 14 d) was required for significant induction of SCD2 mRNA expression compared with that of SCD1. | Clofibric Acid | stearoyl-CoA desaturase | Rattus norvegicus |