Title : Protective effects of 4-phenylbutyrate derivatives on the neuronal cell death and endoplasmic reticulum stress.

Pub. Date : 2012

PMID : 22223342






3 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 4-PBA possesses in vitro chemical chaperone activity and reduces the accumulation of Parkin-associated endothelin receptor-like receptor (Pael-R), which is involved in autosomal recessive juvenile parkinsonism (AR-JP). 4-phenylbutyric acid G protein-coupled receptor 37 Homo sapiens
2 4-PBA possesses in vitro chemical chaperone activity and reduces the accumulation of Parkin-associated endothelin receptor-like receptor (Pael-R), which is involved in autosomal recessive juvenile parkinsonism (AR-JP). 4-phenylbutyric acid G protein-coupled receptor 37 Homo sapiens
3 3-PPA and 4-PBA significantly suppressed neuronal cell death caused by ER stress induced by the overexpression of Pael-R. 4-phenylbutyric acid G protein-coupled receptor 37 Homo sapiens