Pub. Date : 2012 Aug 1
PMID : 22213519
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Altered association of interleukin-6 with sex steroids in lipid metabolism disorder in men with prostate cancer receiving androgen deprivation therapy. | Steroids | interleukin 6 | Homo sapiens |
| 2 | BACKGROUND: Interleukin-6 produced in adipose tissue plays a role in lipid metabolism, and also interacts with sex steroids. | Steroids | interleukin 6 | Homo sapiens |
| 3 | This study was performed to elucidate the mechanism of lipid metabolism disorder during androgen deprivation therapy (ADT) in terms of the association of interleukin-6 with sex steroids. | Steroids | interleukin 6 | Homo sapiens |
| 4 | CONCLUSIONS: Posttreatment interleukin-6 levels had a strong positive correlation with total-testosterone, androstenedione, and estradiol levels, suggesting that a regulation loop may emerge between these sex steroids and interleukin-6 during ADT. | Steroids | interleukin 6 | Homo sapiens |
| 5 | The altered association between interleukin-6 and sex steroids is possibly involved in ADT-related lipid metabolism disorder with unchanged interleukin-6 levels despite increased %body fat. | Steroids | interleukin 6 | Homo sapiens |
| 6 | The altered association between interleukin-6 and sex steroids is possibly involved in ADT-related lipid metabolism disorder with unchanged interleukin-6 levels despite increased %body fat. | Steroids | interleukin 6 | Homo sapiens |