Pub. Date : 2011 Dec
PMID : 22210038
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | LP potently inhibited histamine-induced cytokine production: it (1 x 10(10) CFU per mouse) inhibited IL-4, IL-1beta, and TNF-alpha expression by 88.9%, 88.6%, and 98.9%, respectively. | leucylproline | interleukin 4 | Mus musculus |
| 2 | Based on these findings, LP may improve allergic diseases, such as anaphylaxis, atopic dermatitis, rhinitis, and pruritus by inhibiting the expression of IgE-switching cytokine IL-4 and proinflammatory cytokines IL-1beta and TNF-alpha via NF-kappaB and AP-1 signaling pathways. | leucylproline | interleukin 4 | Mus musculus |