Title : IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1β by keratinocytes via the ROS-NLRP3-caspase-1 pathway.

Pub. Date : 2012 Mar

PMID : 22207130






2 Functional Relationships(s)
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1 IL-17 and IL-22 enhance skin inflammation by stimulating the secretion of IL-1beta by keratinocytes via the ROS-NLRP3-caspase-1 pathway. Reactive Oxygen Species interleukin 1 beta Mus musculus
2 RESULTS: We found that treatment with IL-17 and IL-22 causes an increase in IL-1beta via the activation of NLRP3 by a process that involves the generation of reactive oxygen species. Reactive Oxygen Species interleukin 1 beta Mus musculus