Title : The modulation of the excitability of primary sensory neurons by Ca²⁺-CaM-CaMKII pathway.

Pub. Date : 2012 Oct

PMID : 22205399






2 Functional Relationships(s)
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1 By current clamp recording, we found that the excitability of capsaicin-sensitive small and medium trigeminal ganglion (TG) neurons was significantly reduced by a CaM specific antagonist (W-7) and a CaMKII antagonist (KN-93). Capsaicin calcium/calmodulin dependent protein kinase II gamma Homo sapiens
2 Those evidences show that the excitability of capsaicin sensitive small and medium TG neurons can be regulated by Ca(2+)-CaM-CaMKII pathway through modulating VGSCs and VGPCs. Capsaicin calcium/calmodulin dependent protein kinase II gamma Homo sapiens