Title : Role of structural factors of antitumour anthraquinone derivatives and analogues in the ability to undergo bioreductive activation by NADPH cytochrome P450 reductase: implications for increasing the activity against sensitive and multidrug-resistant leukaemia HL60 cells.

Pub. Date : 2012 Apr

PMID : 22205152






1 Functional Relationships(s)
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1 This suggests that the presence of a modified quinone function is the structural factor excluding reductive activation of antitumour anthraquinone derivatives and analogues by CPR. quinone cytochrome p450 oxidoreductase Homo sapiens