Title : Hypoxic preconditioning increases iron transport rate in astrocytes.

Pub. Date : 2012 Apr

PMID : 22198321






1 Functional Relationships(s)
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1 We herein demonstrated for the first time that HP could induce a significant increase in the expression of HIF-1alpha as well as iron uptake (TfR1 and DMT1) and release (ferroportin1) proteins, and thus increase tansferrin-bound iron (Tf-Fe) and non-transferrin-bound iron (NTBI) uptake and iron release in astrocytes. Hematoporphyrins transferrin receptor Homo sapiens