Title : Effects of dairy consumption on SIRT1 and mitochondrial biogenesis in adipocytes and muscle cells.

Pub. Date : 2011 Dec 20

PMID : 22185590






2 Functional Relationships(s)
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1 Further, direct incubation of physiological concentrations of leucine and its metabolites alpha-Ketoisocaproic acid (KIC) and beta-hydroxy-methylbuteric acid (HMB) with recombinant human SIRT1 enzyme resulted in 30 to 50% increase of SIRT1 activity (p < 0.05). Leucine sirtuin 1 Homo sapiens
2 Further, direct incubation of physiological concentrations of leucine and its metabolites alpha-Ketoisocaproic acid (KIC) and beta-hydroxy-methylbuteric acid (HMB) with recombinant human SIRT1 enzyme resulted in 30 to 50% increase of SIRT1 activity (p < 0.05). Leucine sirtuin 1 Homo sapiens