Title : Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase.

Pub. Date : 2012 Feb 3

PMID : 22184110






2 Functional Relationships(s)
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1 Unrestrained mammalian target of rapamycin complexes 1 and 2 increase expression of phosphatase and tensin homolog deleted on chromosome 10 to regulate phosphorylation of Akt kinase. Sirolimus phosphatase and tensin homolog Homo sapiens
2 To explore the mechanism of PTEN regulation, we used rapamycin and constitutively active mTOR to show that TORC1 increases the expression of PTEN mRNA and protein. Sirolimus phosphatase and tensin homolog Homo sapiens