Title : Melanocortin receptors in rat liver cells: change of gene expression and intracellular localization during acute-phase response.

Pub. Date : 2012 Mar

PMID : 22183812






1 Functional Relationships(s)
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1 Moreover, treatment of isolated liver cells with melanocortin agonists (alpha-MSH and THIQ) inhibited the endotoxin-induced upregulation of the acute-phase cytokine (IL-6, IL1beta and TNF-alpha) gene expression in Kupffer cells and of chemokine gene expression in hepatocytes. 1,2,3,4-tetrahydroisoquinoline interleukin 6 Rattus norvegicus