Pub. Date : 2012 Aug
PMID : 22170686
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | In the present study, 12-O-tetradecanoylphorbol-13-acetate (TPA) addition significantly inhibited GOS-induced apoptosis in human colorectal carcinoma HT-29 cells in accordance with inducing COX-2 protein/PGE(2) production. | Tetradecanoylphorbol Acetate | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 2 | In the present study, 12-O-tetradecanoylphorbol-13-acetate (TPA) addition significantly inhibited GOS-induced apoptosis in human colorectal carcinoma HT-29 cells in accordance with inducing COX-2 protein/PGE(2) production. | Tetradecanoylphorbol Acetate | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |
| 3 | TPA inhibition of GOS-induced apoptosis was blocked by adding protein kinase (PK)C inhibitors including staurosporine (ST), GF109203X (GF), and H7, characterized by the occurrence of cleaved caspase 3 proteins and a decrease in COX-2 protein/PGE(2) production in HT-29 cells. | Tetradecanoylphorbol Acetate | mitochondrially encoded cytochrome c oxidase II | Homo sapiens |