Title : SULF2 methylation is prognostic for lung cancer survival and increases sensitivity to topoisomerase-I inhibitors via induction of ISG15.

Pub. Date : 2012 Sep 13

PMID : 22158045






1 Functional Relationships(s)
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Protein Name
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1 Topotecan, a soluble analog of CPT and FDA-approved anticancer drug, dramatically arrested the growth of SULF2M-ISG15H, but not SULF2U-ISG15L lung tumors in nude mice (P<0.002). Topotecan sulfatase 2 Mus musculus