Title : Acetylation-dependent regulation of mitochondrial ALDH2 activation by SIRT3 mediates acute ethanol-induced eNOS activation.

Pub. Date : 2012 Jan 20

PMID : 22155639






2 Functional Relationships(s)
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1 Here we show that in human aortic endothelial cells (HAECs), rapid activation of mitochondrial aldehyde dehydrogenase 2 (ALDH2) mediates ethanol-induced eNOS activation by preventing reactive oxygen species (ROS) accumulation. Reactive Oxygen Species nitric oxide synthase 3 Homo sapiens
2 Here we show that in human aortic endothelial cells (HAECs), rapid activation of mitochondrial aldehyde dehydrogenase 2 (ALDH2) mediates ethanol-induced eNOS activation by preventing reactive oxygen species (ROS) accumulation. Reactive Oxygen Species nitric oxide synthase 3 Homo sapiens