Title : β-Elemene induces apoptosis as well as protective autophagy in human non-small-cell lung cancer A549 cells.

Pub. Date : 2012 Jan

PMID : 22150682






2 Functional Relationships(s)
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1 Further study showed that beta-elemene inhibited the activity of the PI3K/Akt/mTOR/p70S6K1 signalling pathway, and at the same time it triggered a robust autophagy. beta-elemene AKT serine/threonine kinase 1 Homo sapiens
2 CONCLUSIONS: Our data indicated that beta-elemene inhibited the activity of the PI3K/Akt/mTOR/p70S6K1 signalling pathway in human NSCLC A549 cells, which resulted in apoptosis as well as protective autophagy. beta-elemene AKT serine/threonine kinase 1 Homo sapiens