Pub. Date : 1990 Aug 28
PMID : 2214784
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | An oral antimycotic agent, ketoconazole has been demonstrated to be an inhibitor of cytochrome P-450-dependent monooxygenases. | Ketoconazole | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |
2 | From the binding mode of ketoconazole to cytochrome P-450 and the present findings, it appears likely that the agent binds to a site which is different from that of steroids or pyridine nucleotides. | Ketoconazole | cytochrome P450 family 4 subfamily F member 3 | Homo sapiens |