Title : Inflammasome-IL-1-Th17 response in allergic lung inflammation.

Pub. Date : 2012 Feb

PMID : 22147847






2 Functional Relationships(s)
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1 Recent investigations revealed that airway exposure to allergen in sensitized individuals causes the release of ATP and uric acid, activating the NLRP3 inflammasome complex and cleaving pro-IL-1beta to mature IL-1beta through caspase-1. Uric Acid interleukin 1 beta Mus musculus
2 Recent investigations revealed that airway exposure to allergen in sensitized individuals causes the release of ATP and uric acid, activating the NLRP3 inflammasome complex and cleaving pro-IL-1beta to mature IL-1beta through caspase-1. Uric Acid interleukin 1 beta Mus musculus