Title : Synergistic activity of rapamycin and dexamethasone in vitro and in vivo in acute lymphoblastic leukemia via cell-cycle arrest and apoptosis.

Pub. Date : 2012 Mar

PMID : 22137317






1 Functional Relationships(s)
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1 Compared with either drug alone, dexamethasone+rapamycin showed significantly greater apoptosis and cell cycle arrest in some cell lines, and was more frequently seen in T-lineage cell lines with PTEN mutation. Sirolimus phosphatase and tensin homolog Homo sapiens