Title : MiR-100 resensitizes docetaxel-resistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1.

Pub. Date : 2012 Apr 28

PMID : 22120675






5 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 MiR-100 resensitizes docetaxel-resistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1. Docetaxel ATPase secretory pathway Ca2+ transporting 1 Homo sapiens
2 MiR-100 resensitizes docetaxel-resistant human lung adenocarcinoma cells (SPC-A1) to docetaxel by targeting Plk1. Docetaxel ATPase secretory pathway Ca2+ transporting 1 Homo sapiens
3 By microarray analysis, miR-100 was found significantly down-regulated in docetaxel-resistant SPC-A1/DTX cells compared with parental SPC-A1 cells. Docetaxel ATPase secretory pathway Ca2+ transporting 1 Homo sapiens
4 By microarray analysis, miR-100 was found significantly down-regulated in docetaxel-resistant SPC-A1/DTX cells compared with parental SPC-A1 cells. Docetaxel ATPase secretory pathway Ca2+ transporting 1 Homo sapiens
5 Ectopic miR-100 expression resensitized SPC-A1/DTX cells to docetaxel by suppression of cell proliferation and induction of cell arrest in G(2)/M phase and apoptosis. Docetaxel ATPase secretory pathway Ca2+ transporting 1 Homo sapiens