Pub. Date : 2011
PMID : 22116363
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The anion exchanger pendrin (Pds, SLC26A4) transports various anions including bicarbonate, chloride and iodide. | Chlorides | solute carrier family 26, member 4 | Mus musculus |
| 2 | The anion exchanger pendrin (Pds, SLC26A4) transports various anions including bicarbonate, chloride and iodide. | Chlorides | solute carrier family 26, member 4 | Mus musculus |
| 3 | Genetic ablation of pendrin in mice abolishes luminal chloride-bicarbonate exchanger activity from type B intercalated cells suggesting that pendrin is the apical bicarbonate extruding pathway. | Chlorides | solute carrier family 26, member 4 | Mus musculus |
| 4 | In adult kidney, pendrin expression and activity is regulated by systemic acid-base status, dietary electrolyte intake (mostly chloride), and hormones such as angiotensin II and aldosterone which can affect subcellular localization, the relative number of pendrin expressing cells, and the overall abundance consistent with a role of pendrin in maintaining normal acid-base homeostasis. | Chlorides | solute carrier family 26, member 4 | Mus musculus |