Title : Genetic polymorphisms in metabolic and cellular transport pathway of methotrexate impact clinical outcome of methotrexate monotherapy in Japanese patients with rheumatoid arthritis.

Pub. Date : 2012

PMID : 22104130






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 In conclusion, the ABCB1 3435C>T, ABCB1 2677G>A/T, and MTHFR 1298A>C polymorphisms influenced the efficacy of MTX monotherapy. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens
2 In conclusion, the ABCB1 3435C>T, ABCB1 2677G>A/T, and MTHFR 1298A>C polymorphisms influenced the efficacy of MTX monotherapy. Methotrexate ATP binding cassette subfamily B member 1 Homo sapiens