Title : Both human ferredoxins 1 and 2 and ferredoxin reductase are important for iron-sulfur cluster biogenesis.

Pub. Date : 2012 Feb

PMID : 22101253






1 Functional Relationships(s)
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1 More recently, the roles of these two human ferredoxins in iron-sulfur cluster assembly were assessed, and it was concluded that FDX1 was important solely for its interaction with p450 enzymes to synthesize mitochondrial steroid precursors, whereas FDX2 was used for synthesis of iron-sulfur clusters, but not steroidogenesis. Steroids cytochrome P450 family 2 subfamily B member 6 Homo sapiens