Title : Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite.

Pub. Date : 2012 Mar

PMID : 22100391






3 Functional Relationships(s)
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1 Phosphorylation of the M3/6 dual-specificity phosphatase enhances the activation of JNK by arsenite. arsenite mitogen-activated protein kinase 8 Homo sapiens
2 It has been shown that M3/6 itself is phosphorylated by JNK upon stimulation with arsenite, but the role of this phosphorylation has not been investigated. arsenite mitogen-activated protein kinase 8 Homo sapiens
3 Interestingly, expression of M3/6 phosphorylation mutants delayed the time-course of JNK phosphorylation and activation by arsenite. arsenite mitogen-activated protein kinase 8 Homo sapiens