Title : Increased body mass index after kidney transplantation in activating transcription factor 6 single polymorphism gene carriers.

Pub. Date : 2011 Nov

PMID : 22099811






2 Functional Relationships(s)
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1 Since studies have demonstrated that single nucleotide polymorphisms (SNPs) of ATF6 are associated with type 2 diabetes, we sought to determine whether their mutations were associated with NODAT among renal transplant recipients treated with tacrolimus. Tacrolimus activating transcription factor 6 Homo sapiens
2 However, these data underscore the role of ATF6 and endoplasmic reticulum stress in the regulation of metabolic flux among patients treated with tacrolimus, suggesting that inherited disturbances of endoplasmic reticulum stress signaling could predispose people to obesity. Tacrolimus activating transcription factor 6 Homo sapiens