Pub. Date : 2011 Nov
PMID : 22099811
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Since studies have demonstrated that single nucleotide polymorphisms (SNPs) of ATF6 are associated with type 2 diabetes, we sought to determine whether their mutations were associated with NODAT among renal transplant recipients treated with tacrolimus. | Tacrolimus | activating transcription factor 6 | Homo sapiens |
2 | However, these data underscore the role of ATF6 and endoplasmic reticulum stress in the regulation of metabolic flux among patients treated with tacrolimus, suggesting that inherited disturbances of endoplasmic reticulum stress signaling could predispose people to obesity. | Tacrolimus | activating transcription factor 6 | Homo sapiens |