Pub. Date : 2011 Aug
PMID : 22097737
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | [Effect of ERK1/2 signaling pathway on astragaloside IV protects H9c2 cells against H2O2-induced oxidative injury]. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |
| 2 | Treated with 10 mg/L or 20 mg/L of AST, expression of p-ERK1/2 in H9c2 cells injured from H2O2 was increased significantly (P < 0.01), when PD98059 (inhibitor of ERK1/2) was added, the effects of AST were cancelled. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |
| 3 | CONCLUSION: AST protects H9c2 cells against H2O2-induced oxidative injury partly through ERK1/2 signaling pathway. | Hydrogen Peroxide | mitogen activated protein kinase 3 | Rattus norvegicus |