Title : Mono-(2-ethylhexyl) phthalate directly alters the expression of Leydig cell genes and CYP17 lyase activity in cultured rat fetal testis.

Pub. Date : 2011

PMID : 22087261






1 Functional Relationships(s)
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1 Thus, the hormone data suggested that steroidogenesis was blocked at the level of the 17,20 lyase activity of the P450c17 enzyme (CYP17), converting 17alpha-OHP to androstenedione. Androstenedione cytochrome P450, family 17, subfamily a, polypeptide 1 Rattus norvegicus