Title : Rosuvastatin blocks hERG current and prolongs cardiac repolarization.

Pub. Date : 2012 Feb

PMID : 22081364






1 Functional Relationships(s)
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1 Genetic polymorphisms observed for BCRP, MDR1, and OATP2B1, and IC(50) determined for hERG blocking lead us to propose that some patients may be at risk of rosuvastatin-induced LQTS. Rosuvastatin Calcium ATP binding cassette subfamily B member 1 Homo sapiens