Title : Aldehyde dehydrogenase 1A1 expression in breast cancer is associated with stage, triple negativity, and outcome to neoadjuvant chemotherapy.

Pub. Date : 2012 Mar

PMID : 22080062






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ALDH1A1 inactivates cyclophosphamide, which is an integral agent in breast cancer chemotherapy regimens. Cyclophosphamide aldehyde dehydrogenase 1 family member A1 Homo sapiens
2 The purposes of this study were to verify these results, to correlate ALDH1A1 expression with clinical outcome in patients treated with cyclophosphamide as part of the chemotherapy (adjuvant or neoadjuvant), and to evaluate ALDH1A1 as a useful marker to predict the clinical outcome of breast cancer subsets. Cyclophosphamide aldehyde dehydrogenase 1 family member A1 Homo sapiens