Title : Lubricin is expressed in chondrocytes derived from osteoarthritic cartilage encapsulated in poly (ethylene glycol) diacrylate scaffold.

Pub. Date : 2011

PMID : 22073377






4 Functional Relationships(s)
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Protein Name
Organism
1 Lubricin is expressed in chondrocytes derived from osteoarthritic cartilage encapsulated in poly (ethylene glycol) diacrylate scaffold. poly(ethylene glycol)diacrylate proteoglycan 4 Homo sapiens
2 The expression levels of lubricin were studied by immunohistochemistry: i) in tissue explanted from OA and normal human cartilage; ii) in chondrocytes encapsulated in hydrogel PEGDA from OA and normal human cartilage. poly(ethylene glycol)diacrylate proteoglycan 4 Homo sapiens
3 The chondrocytes from OA cartilage after 5 weeks of culture in hydrogels (PEGDA) showed an increased expression of lubricin compared with the control cartilage. poly(ethylene glycol)diacrylate proteoglycan 4 Homo sapiens
4 The present study demonstrated that OA chondrocytes encapsulated in PEGDA, grown in the scaffold and were able to restore lubricin biosynthesis. poly(ethylene glycol)diacrylate proteoglycan 4 Homo sapiens