Title : COX-2-dependent and -independent biosynthesis of dihydroxy-arachidonic acids in activated human leukocytes.

Pub. Date : 2012 Jan

PMID : 22068350






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Transformation of arachidonic acid was initiated by 5-LOX providing 5S-HETE as a substrate for COX-2 forming 5S,15S-diHETE, 5S,15R-diHETE, and 5S,11R-diHETE as shown by LC/MS and chiral phase HPLC analyses. Arachidonic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens
2 The contribution of COX-2 to the biosynthesis of dihydroxylated derivatives of arachidonic acid provides evidence for functional coupling with 5-LOX in activated human leukocytes. Arachidonic Acid mitochondrially encoded cytochrome c oxidase II Homo sapiens