Title : Molecular pathways: targeting mechanisms of asbestos and erionite carcinogenesis in mesothelioma.

Pub. Date : 2012 Feb 1

PMID : 22065079






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Asbestos induces cell necrosis, causing the release of HMGB1, which in turn may activate Nalp3 inflammasome, a process that is enhanced by asbestos-induced production of reactive oxygen species. Reactive Oxygen Species NLR family pyrin domain containing 3 Homo sapiens