Title : Effect of hCG administration on the relationship between testicular steroids and indolic compounds in fat and plasma in entire male pigs.

Pub. Date : 2006 Feb

PMID : 22061563






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1 Effect of hCG administration on the relationship between testicular steroids and indolic compounds in fat and plasma in entire male pigs. Steroids hypertrichosis 2 (generalised, congenital) Homo sapiens
2 Our objective was to evaluate pigs injected with human chorionic gonadotropin (hCG) as a potential model to study the effect of high testicular steroid levels on the variation in indolic compounds. Steroids hypertrichosis 2 (generalised, congenital) Homo sapiens
3 HCG injection increased the levels of testicular steroids (androstenone, testosterone, dehydroepiandrosterone sulphate, oestrone sulphate and oestrone; p<0.001), and indole levels in plasma and fat (p<0.05). Steroids hypertrichosis 2 (generalised, congenital) Homo sapiens
4 We concluded that hCG-injected pigs might be useful for studying factors responsible for the role of testicular steroids in the occurrence of high indole levels. Steroids hypertrichosis 2 (generalised, congenital) Homo sapiens
5 Pre-selection of sires based on plasma skatole levels affected both the levels of indolic compounds and testicular steroids, especially in fat, which might have suppressed the response to hCG. Steroids hypertrichosis 2 (generalised, congenital) Homo sapiens