Title : Development and preclinical efficacy of novel transforming growth factor-β1 short interfering RNAs for pulmonary fibrosis.

Pub. Date : 2012 Mar

PMID : 22033267






1 Functional Relationships(s)
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1 Intrapulmonary delivery of aerosolized siRNAs of TGF-beta1 with sequences common to humans and rodents significantly inhibited bleomycin-induced pulmonary fibrosis in the acute and chronic phases of the disease and in a dose-dependent manner. Bleomycin transforming growth factor beta 1 Homo sapiens