Title : Ginsenoside Rb1 reverses H2O2-induced senescence in human umbilical endothelial cells: involvement of eNOS pathway.

Pub. Date : 2012 Mar

PMID : 22030897






1 Functional Relationships(s)
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1 H2O2 (40~100 mumol/L) effectively increased SA-beta-gal activity and PAI-1 mRNA levels, two important senescence related biomarkers, in HUVECs, which were dramatically inhibited by Rb1 pre-incubation. Hydrogen Peroxide serpin family E member 1 Homo sapiens