Title : Toll-like receptor 4 promotes tubular inflammation in diabetic nephropathy.

Pub. Date : 2012 Jan

PMID : 22021706






1 Functional Relationships(s)
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1 In vitro, high glucose induced TLR4 expression via protein kinase C activation in a time- and dose-dependent manner, resulting in upregulation of IL-6 and chemokine (C-C motif) ligand 2 (CCL-2) expression via IkappaB/NF-kappaB activation in human proximal tubular epithelial cells. Glucose interleukin 6 Homo sapiens