Pub. Date : 2011 Dec 15
PMID : 22011623
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | However, downregulation of Akt and RIP1/NF-kappaB activity was found to be involved in shikonin-induced apoptosis. | shikonin | nuclear factor kappa B subunit 1 | Homo sapiens |
2 | ROS scavengers blocked shikonin-induced inactivation of Akt and RIP1/NF-kappaB, but Akt or RIP1/NF-kappaB did not regulate ROS generation, suggesting that Akt and RIP1/NF-kappaB signals are downstream of ROS generation. | shikonin | nuclear factor kappa B subunit 1 | Homo sapiens |