Title : Molecular determinants of retinoic acid sensitivity in pancreatic cancer.

Pub. Date : 2012 Jan 1

PMID : 22010213






4 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 RESULTS: Response to ATRA was observed to be dependent upon differential expression of FABP5 versus CRABP2. Tretinoin cellular retinoic acid binding protein 2 Homo sapiens
2 Conversely, CRABP2 expression in the absence of FABP5 was associated with significant tumor growth inhibition with ATRA, even in gemcitabine-resistant tumors. Tretinoin cellular retinoic acid binding protein 2 Homo sapiens
3 The ATRA-resistant phenotype of FABP5(high)CRABP2(null) cells could be circumvented by ectopic expression of CRABP2. Tretinoin cellular retinoic acid binding protein 2 Homo sapiens
4 The ATRA-resistant phenotype of FABP5(high)CRABP2(null) cells could be circumvented by ectopic expression of CRABP2. Tretinoin cellular retinoic acid binding protein 2 Homo sapiens