Title : Endoplasmic reticulum stress does not mediate palmitate-induced insulin resistance in mouse and human muscle cells.

Pub. Date : 2012 Jan

PMID : 22006247






1 Functional Relationships(s)
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1 Indeed, tunicamycin induced a robust activation of the inositol-requiring enzyme 1 (IRE-1)/c-JUN NH2-terminal kinase (JNK) pathway, leading to serine phosphorylation of insulin receptor substrate 1 (IRS-1) and a decrease in IRS-1 tyrosine phosphorylation. Serine mitogen-activated protein kinase 8 Homo sapiens