Title : Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway.

Pub. Date : 2012 Mar 1

PMID : 22004570






2 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 Zyflamend sensitizes tumor cells to TRAIL-induced apoptosis through up-regulation of death receptors and down-regulation of survival proteins: role of ROS-dependent CCAAT/enhancer-binding protein-homologous protein pathway. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens
2 CONCLUSION: Zyflamend potentiates TRAIL-induced apoptosis through the ROS-CHOP-mediated up-regulation of DRs, increase in pro-apoptotic protein and down-regulation of cell survival proteins. Reactive Oxygen Species DNA damage inducible transcript 3 Homo sapiens