Title : Antimalarial activity of a 4',5'-unsaturated 5'-fluoroadenosine mechanism-based inhibitor of S-adenosyl-L-homocysteine hydrolase.

Pub. Date : 1990 Aug 1

PMID : 2200410






1 Functional Relationships(s)
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1 Inhibition of P. berghei growth was associated with a large increase in the concentration of S-adenosyl-L-homocysteine (SAH) in the erythrocytes of the mice treated with MDL 28842. S-Adenosylhomocysteine acyl-CoA synthetase medium-chain family member 3 Mus musculus